96-hour infusion of paclitaxel in advanced bronchioloalveolar carcinoma
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چکیده
منابع مشابه
Phase I trial of 96-hour continuous infusion of dexrazoxane in patients with advanced malignancies.
Dexrazoxane is a bidentate chelator of divalent cations. Pretreatment with short infusions of dexrazoxane prior to bolus doxorubicin has been shown to lessen the incidence and severity of anthracycline-associated cardiac toxicity. However, because of rapid, diffusion-mediated cellular uptake and the short plasma half-life of dexrazoxane, combined with prolonged cellular retention of doxorubicin...
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The present study was conducted to compare the pharmacokinetics and pharmacodynamics (PD) of paclitaxel between Phase I trials of 3- and 24-h infusions and to determine the most informative pharmacokinetic parameter to describe the PD. Twenty-seven patients were treated in a Phase I study of paclitaxel by a 3-h infusion at one of six doses: 105, 135, 180, 210, 240, and 270 mg/m2. Pharmacokineti...
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Our purpose was to determine the antitumor efficacy and safety profile of the combination of paclitaxel administered by 96-h continuous i.v. infusion followed by bolus cisplatin in patients with untreated advanced non-small cell lung cancer (NSCLC). Fifty-eight patients with untreated advanced or recurrent NSCLC were enrolled between October 1995 and December 1998. The median patient age was 60...
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1 Beck-Sague C, Dooley SW, Hutton MD, et al. Hospital outbreak of multidrug-resistant Mycobacterium tuberculosis infections: factors in transmission to staff and HIV-infected patients. JAMA 1992; 268:1280-86 2 Pierce JR, Sims SL, Holman GH. Tranasmission oftuberculosis to hospital workers by a patient with AIDS. Chest 1992; 101:581-82 3 Centers for Disease Control and Prevention. Nosocomial tra...
متن کاملFormer Mucinous Bronchioloalveolar Carcinoma Revisited
This is a brief case report of invasive multicentric mucinous adenocarcinoma presented at a rather young age with bronchorrhea and persistent consolidation that ended up with the patient demise; nevertheless, we demonstrate relevant radiological and pathological features with emphasis on the new classification of bronchioloalveolar carcinoma, a term that should no longer be in use.
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ژورنال
عنوان ژورنال: Nature Clinical Practice Oncology
سال: 2005
ISSN: 1743-4254,1743-4262
DOI: 10.1038/ncponc0258